Botox Is An Effective Treatment for Excessive Sweating
American Family Physician, May 15, 2001 by Nicholas J. Lowe
(59th Annual Meeting of the American Academy of Dermatology) Results of two clinical trials suggest that injections of botulinum toxin type A (Botox) can decrease perspiration at the injected area by inhibiting the release of the neurotransmitter responsible for stimulating the sweat gland in patients with palmar hyperhidrosis (excessive sweating of the palms) and axillary hyperhidrosis (excessive sweating under the arms). In a double-blind study, 19 patients with primary palmar hyperhidrosis were randomly assigned to receive placebo in one palm and a one-time treatment of 15 injections of 0.1 mL of Botox in the other palm. After 28 days, patients' ratings of clinical severity were significantly lower in the palm receiving Botox compared with the palm receiving placebo. All of the patients rated the Botox injections as "successful" at reducing the amount of perspiration, while 12 percent of patients believed the placebo injection had been successful. Patients experienced no serious adverse events, and there was no significant weakness in the hands because the Botox injection did not go deeper than the skin. In another study, 320 patients were randomized in a 3:1 ratio to receive 50 u of Botox or placebo as 2 mL injections in each armpit. After four weeks, 93.8 percent of patients treated with Botox experienced a 50 percent or greater reduction in sweat production, compared with 35.9 percent of patients in the placebo group. The mean percentage in the reduction of sweat production was 83.5 percent in patients receiving Botox and 20.8 percent in patients receiving placebo, and mean patient satisfaction was significantly higher in patients receiving Botox. Patients in both groups experienced a low occurrence of adverse events.--NICHOLAS J. LOWE, M.D., University of California-Los Angeles School of Medicine, Los Angeles, California.
COPYRIGHT 2001 American Academy of Family Physicians
COPYRIGHT 2001 Gale Group
Hyperhidrosis or Excessive Sweating
What is hyperhidrosis?
Where does hyperhidrosis occur?
What are the symptoms of hyperhidrosis?
What are the alternative treatments for hyperhidrosis?
Is there a surgical treatment for hyperhidrosis?
|
Boston, Massachussetts
"It's so awesome! I'm really glad I went to cure my hyperhidrosis. It's great to be able to go to the gym
and not sweat on my hands, face, head, or feet. Thank you so much!" |
Reno, Nevada
"Thank you, for curing of my hyperhidrosis. Your staff was compassionate, caring,
and very professional. You made me feel like family. I was attended to in a prompt and hospitable manner.
Everything was thoroughly explained in detail to me. I can't wait to tell everyone how successful my
surgery was! You are definitely a |
|
Irvine, California
"As a little boy, I already had sweaty palms. I was miserable because this condition
had been with me all my life. I dreaded attending church or social gatherings
because it meant I had to face others. Also, I had difficulty handling tools at
work because everything I touched became wet. I am very happy with the result
of my surgery. Thanks for curing my hyperhidrosis. I feel years
younger. I highly recommend Hyperhidrosis Center™ to anyone who is suffering from palmar hyperhidrosis."
|
Helena, Montana
"I tried medicines--from Beta Blockers--to lotions--to antipsychotics, but to no avail.
I was using Drysol. At the beginning it was great. I had dry hands for two
weeks in- between doses. Then slowly, the medication started to lose its affect
on me. Instead of applying once every two weeks it was once every two days.
I started to look on the Internet for other alternatives and found the website for the treating hyperhidrosis."
|
|
Waikiki, Hawaii "I strongly suggest that anyone suffering from sweaty palms should consult
the doctor to have the surgery. I suffered from this problem for more than
20 years, and now there is no more hyperhidrosis." |
Houston, Texas "I am very happy to come to California to have removal of my hyperhidrosis. Both my hands and feet are now dry. If anyone in
the Houston, Texas area would like to talk with me, it's okay. Please
call Hyperhidrosis Center™ at 1-866-PALM-911 for my number."
|
